Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer's disease by remodeling peri-plaque...
Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer's disease by remodeling peri-plaque astrocyte structure
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Redistribution of the water channel aquaporin-4 (AQP4) away from astrocyte endfeet and into parenchymal processes is a striking histological feature in mouse models of Alzheimer's disease (AD) and other neurological conditions with prominent astrogliosis. AQP4 redistribution has been proposed to impair bulk Aβ clearance in AD, resulting in increase...
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Full title
Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer's disease by remodeling peri-plaque astrocyte structure
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TN_cdi_doaj_primary_oai_doaj_org_article_10d43df501334b6989400e71771dc976
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_10d43df501334b6989400e71771dc976
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-019-0728-0
