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Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling

Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_10ed8a7c18e849f5abc41f2314e40880

Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling

About this item

Full title

Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling

Publisher

Hoboken, USA: John Wiley & Sons, Inc

Journal title

Laryngoscope Investigative Otolaryngology, 2024-02, Vol.9 (1), p.e1219-n/a

Language

English

Formats

Publication information

Publisher

Hoboken, USA: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Objectives
Approximately 25% of Americans suffer from laryngopharyngeal reflux (LPR), a disease for which no effective medical therapy exists. Pepsin is a predominant source of damage during LPR and a key therapeutic target. Fosamprenavir (FOS) inhibits pepsin and prevents damage in an LPR mouse model. Inhaled FOS protects at a lower dose than o...

Alternative Titles

Full title

Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_10ed8a7c18e849f5abc41f2314e40880

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_10ed8a7c18e849f5abc41f2314e40880

Other Identifiers

ISSN

2378-8038

E-ISSN

2378-8038

DOI

10.1002/lio2.1219

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