Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling
Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling
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Publisher
Hoboken, USA: John Wiley & Sons, Inc
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Language
English
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Publisher
Hoboken, USA: John Wiley & Sons, Inc
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Objectives
Approximately 25% of Americans suffer from laryngopharyngeal reflux (LPR), a disease for which no effective medical therapy exists. Pepsin is a predominant source of damage during LPR and a key therapeutic target. Fosamprenavir (FOS) inhibits pepsin and prevents damage in an LPR mouse model. Inhaled FOS protects at a lower dose than o...
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Full title
Inhaled fosamprenavir for laryngopharyngeal reflux: Toxicology and fluid dynamics modeling
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TN_cdi_doaj_primary_oai_doaj_org_article_10ed8a7c18e849f5abc41f2314e40880
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_10ed8a7c18e849f5abc41f2314e40880
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ISSN
2378-8038
E-ISSN
2378-8038
DOI
10.1002/lio2.1219