Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in...
Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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In mammalian cells genes that are in close proximity can be transcriptionally coupled: silencing or activating one gene can affect its neighbors. Understanding these dynamics is important for natural processes, such as heterochromatin spreading during development and aging, and when designing synthetic gene regulation circuits. Here, we systematica...
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Full title
Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells
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TN_cdi_doaj_primary_oai_doaj_org_article_10f76403709a4bd3b4ad4fbed615dccd
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_10f76403709a4bd3b4ad4fbed615dccd
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.75115
