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A mitochondrial megachannel resides in monomeric F1FO ATP synthase

A mitochondrial megachannel resides in monomeric F1FO ATP synthase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1114e6356c4045608f3cc3526a4d63ca

A mitochondrial megachannel resides in monomeric F1FO ATP synthase

About this item

Full title

A mitochondrial megachannel resides in monomeric F1FO ATP synthase

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-12, Vol.10 (1), p.1-11, Article 5823

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Purified mitochondrial ATP synthase has been shown to form Ca
2+
-activated, large conductance channel activity similar to that of mitochondrial megachannel (MMC) or mitochondrial permeability transition pore (mPTP) but the oligomeric state required for channel formation is being debated. We reconstitute purified monomeric ATP synthase from p...

Alternative Titles

Full title

A mitochondrial megachannel resides in monomeric F1FO ATP synthase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1114e6356c4045608f3cc3526a4d63ca

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1114e6356c4045608f3cc3526a4d63ca

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-13766-2

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