Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer
Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer
About this item
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Author / Creator
Coutzac, Clélia , Jouniaux, Jean-Mehdi , Paci, Angelo , Schmidt, Julien , Mallardo, Domenico , Seck, Atmane , Asvatourian, Vahe , Cassard, Lydie , Saulnier, Patrick , Lacroix, Ludovic , Woerther, Paul-Louis , Vozy, Aurore , Naigeon, Marie , Nebot-Bral, Laetitia , Desbois, Mélanie , Simeone, Ester , Mateus, Christine , Boselli, Lisa , Grivel, Jonathan , Soularue, Emilie , Lepage, Patricia , Carbonnel, Franck , Ascierto, Paolo Antonio , Robert, Caroline and Chaput, Nathalie
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Gut microbiota composition influences the clinical benefit of immune checkpoints in patients with advanced cancer but mechanisms underlying this relationship remain unclear. Molecular mechanism whereby gut microbiota influences immune responses is mainly assigned to gut microbial metabolites. Short-chain fatty acids (SCFA) are produced in large amo...
Alternative Titles
Full title
Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer
Authors, Artists and Contributors
Author / Creator
Jouniaux, Jean-Mehdi
Paci, Angelo
Schmidt, Julien
Mallardo, Domenico
Seck, Atmane
Asvatourian, Vahe
Cassard, Lydie
Saulnier, Patrick
Lacroix, Ludovic
Woerther, Paul-Louis
Vozy, Aurore
Naigeon, Marie
Nebot-Bral, Laetitia
Desbois, Mélanie
Simeone, Ester
Mateus, Christine
Boselli, Lisa
Grivel, Jonathan
Soularue, Emilie
Lepage, Patricia
Carbonnel, Franck
Ascierto, Paolo Antonio
Robert, Caroline
Chaput, Nathalie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1117fcdf2fd44e30b8bbaa1e829d3ecf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1117fcdf2fd44e30b8bbaa1e829d3ecf
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-16079-x
