Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expressi...
Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis
About this item
Full title
Author / Creator
Hu, Dan , Notarbartolo, Samuele , Croonenborghs, Tom , Patel, Bonny , Cialic, Ron , Yang, Tun-Hsiang , Aschenbrenner, Dominik , Andersson, Karin M. , Gattorno, Marco , Pham, Minh , Kivisakk, Pia , Pierre, Isabelle V. , Lee, Youjin , Kiani, Karun , Bokarewa, Maria , Tjon, Emily , Pochet, Nathalie , Sallusto, Federica , Kuchroo, Vijay K. and Weiner, Howard L.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
We have previously reported the molecular signature of murine pathogenic T
H
17 cells that induce experimental autoimmune encephalomyelitis (EAE) in animals. Here we show that human peripheral blood IFN-γ
+
IL-17
+
(T
H
1/17) and IFN-γ
−
IL-17
+
(T
H
17) CD4
+
T cells display distinct transcriptional...
Alternative Titles
Full title
Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis
Authors, Artists and Contributors
Author / Creator
Notarbartolo, Samuele
Croonenborghs, Tom
Patel, Bonny
Cialic, Ron
Yang, Tun-Hsiang
Aschenbrenner, Dominik
Andersson, Karin M.
Gattorno, Marco
Pham, Minh
Kivisakk, Pia
Pierre, Isabelle V.
Lee, Youjin
Kiani, Karun
Bokarewa, Maria
Tjon, Emily
Pochet, Nathalie
Sallusto, Federica
Kuchroo, Vijay K.
Weiner, Howard L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_11569c6b2d2b489ab5a6e3fe5796dc19
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_11569c6b2d2b489ab5a6e3fe5796dc19
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01571-8
