NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal...
NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal degradation pathway
About this item
Full title
Author / Creator
Cui, Shuzhi , Xia, Tian , Zhao, Jianjin , Ren, Xiaoyu , Wu, Tingtao , Kameni, Mireille , Guo, Xiaoju , He, Li , Guo, Jingao , Duperray-Susini, Aléria , Levillayer, Florence , Collard, Jean-Marc , Zhong, Jin , Pan, Lifeng , Tangy, Frédéric , Vidalain, Pierre-Olivier , Zhou, Dongming , Jiu, Yaming , Faure, Mathias and Wei, Yu
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Autophagy receptor NDP52 triggers bacterial autophagy against infection. However, the ability of NDP52 to protect against viral infection has not been established. We show that NDP52 binds to envelope proteins of hepatitis B virus (HBV) and triggers a degradation process that promotes HBV clearance. Inactivating NDP52 in hepatocytes results in decr...
Alternative Titles
Full title
NDP52 mediates an antiviral response to hepatitis B virus infection through Rab9-dependent lysosomal degradation pathway
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_118bc231fbab423e8611f082d27454bf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_118bc231fbab423e8611f082d27454bf
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-44201-2
