Activating hidden signals by mimicking cryptic sites in a synthetic extracellular matrix
Activating hidden signals by mimicking cryptic sites in a synthetic extracellular matrix
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cryptic sites are short signaling peptides buried within the native extracellular matrix (ECM). Enzymatic cleavage of an ECM protein reveals these hidden peptide sequences, which interact with surface receptors to control cell behavior. Materials that mimic this dynamic interplay between cells and their surroundings via cryptic sites could enable a...
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Activating hidden signals by mimicking cryptic sites in a synthetic extracellular matrix
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TN_cdi_doaj_primary_oai_doaj_org_article_11a43ebb99834ecb811c4f5d4abaf2b3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_11a43ebb99834ecb811c4f5d4abaf2b3
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39349-w
