Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immuno...
Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice
About this item
Full title
Author / Creator
Hu, Xiaomeng , Manner, Karl , DeJesus, Rowena , White, Kathy , Gattis, Corie , Ngo, Priscilla , Bandoro, Christopher , Tham, Eleonore , Chu, Elaine Y. , Young, Chi , Wells, Frank , Basco, Ronald , Friera, Annabelle , Kangeyan, Divy , Beauchesne, Pascal , Dowdle, William E. , Deuse, Tobias , Fry, Terry J. , Foster, Aaron E. and Schrepfer, Sonja
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Manufacturing autologous chimeric antigen receptor (CAR) T cell therapeutics is complex, and many patients experience treatment delays or cannot be treated at all. Although current allogeneic CAR products have the potential to overcome manufacturing bottlenecks, they are subject to immune rejection and failure to persist in the host, and thus do no...
Alternative Titles
Full title
Hypoimmune anti-CD19 chimeric antigen receptor T cells provide lasting tumor control in fully immunocompetent allogeneic humanized mice
Authors, Artists and Contributors
Author / Creator
Manner, Karl
DeJesus, Rowena
White, Kathy
Gattis, Corie
Ngo, Priscilla
Bandoro, Christopher
Tham, Eleonore
Chu, Elaine Y.
Young, Chi
Wells, Frank
Basco, Ronald
Friera, Annabelle
Kangeyan, Divy
Beauchesne, Pascal
Dowdle, William E.
Deuse, Tobias
Fry, Terry J.
Foster, Aaron E.
Schrepfer, Sonja
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_11a7498d8b624c7f9293ade72a94e6d3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_11a7498d8b624c7f9293ade72a94e6d3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-37785-2
