ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics
ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics
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Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is caused by
NOTCH3
mutations. Typical CADASIL is characterised by subcortical ischemic strokes due to severe arteriopathy and fibrotic thickening of small arteries. Arteriolar vascular smooth muscle cells (VSMCs) are the key target in CADASIL...
Alternative Titles
Full title
ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_11dce6bfaaa44fa2b8315fb967bc1c18
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_11dce6bfaaa44fa2b8315fb967bc1c18
Other Identifiers
ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-023-01558-1
