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Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1226adb34adc4634871fcd9db63032d8

Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

About this item

Full title

Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-01, Vol.12 (1), p.447-447, Article 447

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cerebrospinal fluid (CSF) provides vital support for the brain. Abnormal CSF accumulation, such as hydrocephalus, can negatively affect perinatal neurodevelopment. The mechanisms regulating CSF clearance during the postnatal critical period are unclear. Here, we show that CSF K
+
, accompanied by water, is cleared through the choroid plexus (...

Alternative Titles

Full title

Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_1226adb34adc4634871fcd9db63032d8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1226adb34adc4634871fcd9db63032d8

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-20666-3

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