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Progranulin sustains STAT3 hyper‐activation and oncogenic function in colorectal cancer cells

Progranulin sustains STAT3 hyper‐activation and oncogenic function in colorectal cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_124e3a886d294b1987dbedcafaddeff2

Progranulin sustains STAT3 hyper‐activation and oncogenic function in colorectal cancer cells

About this item

Full title

Progranulin sustains STAT3 hyper‐activation and oncogenic function in colorectal cancer cells

Publisher

United States: John Wiley & Sons, Inc

Journal title

Molecular oncology, 2019-10, Vol.13 (10), p.2142-2159

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Persistent activation of Signal Transducer and Activator of Transcription (STAT)3 occurs in a high percentage of tumors, including colorectal cancer (CRC), thereby contributing to malignant cell proliferation and survival. Although STAT3 is recognized as an attractive therapeutic target in CRC, conventional approaches aimed at inhibiting its functi...

Alternative Titles

Full title

Progranulin sustains STAT3 hyper‐activation and oncogenic function in colorectal cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_124e3a886d294b1987dbedcafaddeff2

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_124e3a886d294b1987dbedcafaddeff2

Other Identifiers

ISSN

1574-7891,1878-0261

E-ISSN

1878-0261

DOI

10.1002/1878-0261.12552

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