Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and...
Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles
About this item
Full title
Author / Creator
Flynn, Aidan , Pattison, Andrew D. , Balachander, Shiva , Boehm, Emma , Bowen, Blake , Dwight, Trisha , Rossello, Fernando J. , Hofmann, Oliver , Martelotto, Luciano , Zethoven, Maia , Kirschner, Lawrence S. , Else, Tobias , Fishbein, Lauren , Gill, Anthony J. , Tischler, Arthur S. , Giordano, Thomas , Prodanov, Tamara , Noble, Jane R. , Reddel, Roger R. , Trainer, Alison H. , Ghayee, Hans Kumar , Bourdeau, Isabelle , Elston, Marianne , Ishak, Diana , Ngeow Yuen Yie, Joanne , Hicks, Rodney J. , Crona, Joakim , Åkerström, Tobias , Stålberg, Peter , Dahia, Patricia , Grimmond, Sean , Clifton-Bligh, Roderick , Pacak, Karel and Tothill, Richard W.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Hereditary
SDHB
-mutant pheochromocytomas (PC) and paragangliomas (PG) are rare tumours with a high propensity to metastasize although their clinical behaviour is unpredictable. To characterize the genomic landscape of these tumours and identify metastasis biomarkers, we perform multi-omic analysis on 94 tumours from 79 patients using seven m...
Alternative Titles
Full title
Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles
Authors, Artists and Contributors
Author / Creator
Pattison, Andrew D.
Balachander, Shiva
Boehm, Emma
Bowen, Blake
Dwight, Trisha
Rossello, Fernando J.
Hofmann, Oliver
Martelotto, Luciano
Zethoven, Maia
Kirschner, Lawrence S.
Else, Tobias
Fishbein, Lauren
Gill, Anthony J.
Tischler, Arthur S.
Giordano, Thomas
Prodanov, Tamara
Noble, Jane R.
Reddel, Roger R.
Trainer, Alison H.
Ghayee, Hans Kumar
Bourdeau, Isabelle
Elston, Marianne
Ishak, Diana
Ngeow Yuen Yie, Joanne
Hicks, Rodney J.
Crona, Joakim
Åkerström, Tobias
Stålberg, Peter
Dahia, Patricia
Grimmond, Sean
Clifton-Bligh, Roderick
Pacak, Karel
Tothill, Richard W.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_1255e7aad4c7416ca828fa70da730326
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1255e7aad4c7416ca828fa70da730326
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57595-y