Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin c...
Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin clearance
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Author / Creator
Zheng, Lili , Jia, Junqiu , Chen, Yan , Liu, Renyuan , Cao, Runjing , Duan, Manlin , Zhang, Meijuan and Xu, Yun
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Vascular dementia (VAD) is the second most common type of dementia lacking effective treatments. Pentoxifylline (PTX), a nonselective phosphodiesterase inhibitor, displays protective effects in multiple cerebral diseases. In this study, we aimed to investigate the therapeutic effects and potential mechanisms of PTX in VAD.
Bilateral common carot...
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Full title
Pentoxifylline alleviates ischemic white matter injury through up-regulating Mertk-mediated myelin clearance
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_125c22dc5c4c435c863b8450ee8af4ed
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_125c22dc5c4c435c863b8450ee8af4ed
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-022-02480-4