Targeting chondrocytes for arresting bony fusion in ankylosing spondylitis
Targeting chondrocytes for arresting bony fusion in ankylosing spondylitis
About this item
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Author / Creator
Shao, Fenli , Liu, Qianqian , Zhu, Yuyu , Fan, Zhidan , Chen, Wenjun , Liu, Shijia , Li, Xiaohui , Guo, Wenjie , Feng, Gen-Sheng , Yu, Haiguo , Xu, Qiang and Sun, Yang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Bony fusion caused by pathological new bone formation manifests the clinical feature of ankylosing spondylitis (AS). However, the underlying mechanism remains elusive. Here we discovered spontaneous kyphosis, arthritis and bony fusion in mature CD4-Cre;
Ptpn11
f/f
mice, which present the pathophysiological features of AS. A population of C...
Alternative Titles
Full title
Targeting chondrocytes for arresting bony fusion in ankylosing spondylitis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_12886a3b76044df8b6656dcdbe796a6e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_12886a3b76044df8b6656dcdbe796a6e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-26750-6
