MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF pro...
MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner
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England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Fibroblasts are crucial mediators of tumor-stroma cross-talk through synthesis and remodeling of the extracellular matrix and production of multiple soluble factors. Nonetheless, little is still known about specific determinants of fibroblast pro-tumorigenic activity in lung cancer. Here, we aimed at understanding the role of miRNAs, which are ofte...
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Full title
MiR-16 regulates the pro-tumorigenic potential of lung fibroblasts through the inhibition of HGF production in an FGFR-1- and MEK1-dependent manner
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TN_cdi_doaj_primary_oai_doaj_org_article_129bb9357c5543c1a5ce2d32753e0fd9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_129bb9357c5543c1a5ce2d32753e0fd9
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-018-0594-4
