FLT3/ITD Associated with an Immature Immunophenotype in PML-RARα Leukemia
FLT3/ITD Associated with an Immature Immunophenotype in PML-RARα Leukemia
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Publisher
Italy: MDPI AG
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Language
English
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Publisher
Italy: MDPI AG
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Contents
Acute promyelocytic leukemia (APL) is characterized by the specific PML-RARa fusion gene resulting from translocation t(15;17) (q22;q12). Internal tandem duplication (ITD) of the FLT3 gene has been observed in approximately 35% of APLs, and large-scale studies have identified the presence of ITD as an adverse prognostic factor for acute myeloblasti...
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Full title
FLT3/ITD Associated with an Immature Immunophenotype in PML-RARα Leukemia
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TN_cdi_doaj_primary_oai_doaj_org_article_12a7c1c8dfb44b99a4d77d301a47cf27
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_12a7c1c8dfb44b99a4d77d301a47cf27
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ISSN
2038-8330,2038-8322
E-ISSN
2038-8330
DOI
10.4081/hr.2012.e22
