Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breas...
Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer
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Author / Creator
Jiang, Huimin , Wei, Huimin , Wang, Hang , Wang, Zhaoyang , Li, Jianjun , Ou, Yang , Xiao, Xuechun , Wang, Wenhao , Chang, Antao , Sun, Wei , Zhao, Li and Yang, Shuang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Aerobic glycolysis (the Warburg effect) has been demonstrated to facilitate tumor progression by producing lactate, which has important roles as a proinflammatory and immunosuppressive mediator. However, how aerobic glycolysis is directly regulated is largely unknown. Here, we show that ectopic Zeb1 directly increases the transcriptional expression...
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Full title
Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_12ab605f4b3f42a7adaf2cb8b0997ef0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_12ab605f4b3f42a7adaf2cb8b0997ef0
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-022-04632-z
