Common diseases alter the physiological age-related blood microRNA profile
Common diseases alter the physiological age-related blood microRNA profile
About this item
Full title
Author / Creator
Fehlmann, Tobias , Lehallier, Benoit , Schaum, Nicholas , Hahn, Oliver , Kahraman, Mustafa , Li, Yongping , Grammes, Nadja , Geffers, Lars , Backes, Christina , Balling, Rudi , Kern, Fabian , Krüger, Rejko , Lammert, Frank , Ludwig, Nicole , Meder, Benjamin , Fromm, Bastian , Maetzler, Walter , Berg, Daniela , Brockmann, Kathrin , Deuschle, Christian , von Thaler, Anna-Katharina , Eschweiler, Gerhard W. , Milman, Sofiya , Barziliai, Nir , Reichert, Matthias , Wyss-Coray, Tony , Meese, Eckart and Keller, Andreas
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-transcriptional gene silencing through base-pair binding on their target mRNAs. We identified nonlinear changes in age-related microRNAs by analyzing whole blood from 1334 healthy individuals. We observed a larger influence of the age as compared to the sex and...
Alternative Titles
Full title
Common diseases alter the physiological age-related blood microRNA profile
Authors, Artists and Contributors
Author / Creator
Lehallier, Benoit
Schaum, Nicholas
Hahn, Oliver
Kahraman, Mustafa
Li, Yongping
Grammes, Nadja
Geffers, Lars
Backes, Christina
Balling, Rudi
Kern, Fabian
Krüger, Rejko
Lammert, Frank
Ludwig, Nicole
Meder, Benjamin
Fromm, Bastian
Maetzler, Walter
Berg, Daniela
Brockmann, Kathrin
Deuschle, Christian
von Thaler, Anna-Katharina
Eschweiler, Gerhard W.
Milman, Sofiya
Barziliai, Nir
Reichert, Matthias
Wyss-Coray, Tony
Meese, Eckart
Keller, Andreas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_132c3d783c2f4f77b4984be2f3b3481b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_132c3d783c2f4f77b4984be2f3b3481b
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-19665-1
