Microfluidic live tracking and transcriptomics of cancer-immune cell doublets link intercellular pro...
Microfluidic live tracking and transcriptomics of cancer-immune cell doublets link intercellular proximity and gene regulation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cell–cell communication and physical interactions play a vital role in cancer initiation, homeostasis, progression, and immune response. Here, we report a system that combines live capture of different cell types, co-incubation, time-lapse imaging, and gene expression profiling of doublets using a microfluidic integrated fluidic circuit that enable...
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Microfluidic live tracking and transcriptomics of cancer-immune cell doublets link intercellular proximity and gene regulation
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TN_cdi_doaj_primary_oai_doaj_org_article_1332145f194e41f78d1b27d11c29bdd9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1332145f194e41f78d1b27d11c29bdd9
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2399-3642
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2399-3642
DOI
10.1038/s42003-022-04205-y