RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structur...
RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure
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Author / Creator
Solomon, Oz , Di Segni, Ayelet , Cesarkas, Karen , Porath, Hagit T. , Marcu-Malina, Victoria , Mizrahi, Orel , Stern-Ginossar, Noam , Kol, Nitzan , Farage-Barhom, Sarit , Glick-Saar, Efrat , Lerenthal, Yaniv , Levanon, Erez Y. , Amariglio, Ninette , Unger, Ron , Goldstein, Itamar , Eyal, Eran and Rechavi, Gidi
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Adenosine deaminase acting on RNA 1 (ADAR1) is the master RNA editor, catalyzing the deamination of adenosine to inosine. RNA editing is vital for preventing abnormal activation of cytosolic nucleic acid sensing pathways by self-double-stranded RNAs. Here we determine, by parallel analysis of RNA secondary structure sequencing (PARS-seq), the globa...
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Full title
RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure
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TN_cdi_doaj_primary_oai_doaj_org_article_135bc3a86dbd4e62a8694058deaacfb0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_135bc3a86dbd4e62a8694058deaacfb0
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01458-8
