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RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structur...

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structur...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_135bc3a86dbd4e62a8694058deaacfb0

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure

About this item

Full title

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-11, Vol.8 (1), p.1440-14, Article 1440

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Adenosine deaminase acting on RNA 1 (ADAR1) is the master RNA editor, catalyzing the deamination of adenosine to inosine. RNA editing is vital for preventing abnormal activation of cytosolic nucleic acid sensing pathways by self-double-stranded RNAs. Here we determine, by parallel analysis of RNA secondary structure sequencing (PARS-seq), the globa...

Alternative Titles

Full title

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_135bc3a86dbd4e62a8694058deaacfb0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_135bc3a86dbd4e62a8694058deaacfb0

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-01458-8

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