Dynamics and Molecular Interactions of GPI-Anchored CD59
Dynamics and Molecular Interactions of GPI-Anchored CD59
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Contents
CD59 is a GPI-anchored cell surface receptor that serves as a gatekeeper to controlling pore formation. It is the only membrane-bound inhibitor of the complement membrane attack complex (MAC), an immune pore that can damage human cells. While CD59 blocks MAC pores, the receptor is co-opted by bacterial pore-forming proteins to target human cells. R...
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Full title
Dynamics and Molecular Interactions of GPI-Anchored CD59
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TN_cdi_doaj_primary_oai_doaj_org_article_13649c1349d443119008cb6bad20ff67
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13649c1349d443119008cb6bad20ff67
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ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins15070430