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Dynamics and Molecular Interactions of GPI-Anchored CD59

Dynamics and Molecular Interactions of GPI-Anchored CD59

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13649c1349d443119008cb6bad20ff67

Dynamics and Molecular Interactions of GPI-Anchored CD59

About this item

Full title

Dynamics and Molecular Interactions of GPI-Anchored CD59

Publisher

Switzerland: MDPI AG

Journal title

Toxins, 2023-06, Vol.15 (7), p.430

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

CD59 is a GPI-anchored cell surface receptor that serves as a gatekeeper to controlling pore formation. It is the only membrane-bound inhibitor of the complement membrane attack complex (MAC), an immune pore that can damage human cells. While CD59 blocks MAC pores, the receptor is co-opted by bacterial pore-forming proteins to target human cells. R...

Alternative Titles

Full title

Dynamics and Molecular Interactions of GPI-Anchored CD59

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_13649c1349d443119008cb6bad20ff67

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13649c1349d443119008cb6bad20ff67

Other Identifiers

ISSN

2072-6651

E-ISSN

2072-6651

DOI

10.3390/toxins15070430

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