The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function
The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function
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Zhang, Weidong , Miura, Ayako , Abu Saleh, Md Moin , Shimizu, Koichiro , Mita, Yuichiro , Tanida, Ryota , Hirako, Satoshi , Shioda, Seiji , Gmyr, Valery , Kerr-Conte, Julie , Pattou, Francois , Jin, Chunhuan , Kanai, Yoshikatsu , Sasaki, Kazuki , Minamino, Naoto , Sakoda, Hideyuki and Nakazato, Masamitsu
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Insulin secretion from pancreatic β cells is regulated by multiple stimuli, including nutrients, hormones, neuronal inputs, and local signalling. Amino acids modulate insulin secretion via amino acid transporters expressed on β cells. The granin protein VGF has dual roles in β cells: regulating secretory granule formation and functioning as a multi...
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Full title
The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function
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TN_cdi_doaj_primary_oai_doaj_org_article_13b28fe0aa5b471fb9ba3b62af44728f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13b28fe0aa5b471fb9ba3b62af44728f
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-43976-8
