Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse...
Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache
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London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Medication-overuse headaches (MOH) occur with both over-the-counter and pain-relief medicines, including paracetamol, opioids and combination analgesics. The mechanisms that lead to MOH are still uncertain. Here, we show that abnormal activation of Nav1.9 channels by Nitric Oxide (NO) is responsible for MOH induced by triptan migraine medicine. Del...
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Full title
Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache
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TN_cdi_doaj_primary_oai_doaj_org_article_13bb724449b94f508ae02468f5087389
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13bb724449b94f508ae02468f5087389
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12197-3
