Cystin genetic variants cause autosomal recessive polycystic kidney disease associated with altered...
Cystin genetic variants cause autosomal recessive polycystic kidney disease associated with altered Myc expression
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Mutation of the
Cys1
gene underlies the renal cystic disease in the
Cys1
cpk/cpk
(
cpk
) mouse that phenocopies human autosomal recessive polycystic kidney disease (ARPKD). Cystin, the protein product of
Cys1
, is expressed in the primary apical cilia of renal ductal epithelial cells. In previous studies, we showed that c...
Alternative Titles
Full title
Cystin genetic variants cause autosomal recessive polycystic kidney disease associated with altered Myc expression
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_13bb7bdf8ff344ba8c2f370bc275a2ab
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13bb7bdf8ff344ba8c2f370bc275a2ab
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-97046-4
