Determinants of genome-wide distribution and evolution of uORFs in eukaryotes
Determinants of genome-wide distribution and evolution of uORFs in eukaryotes
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Author / Creator
Zhang, Hong , Wang, Yirong , Wu, Xinkai , Tang, Xiaolu , Wu, Changcheng and Lu, Jian
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Upstream open reading frames (uORFs) play widespread regulatory functions in modulating mRNA translation in eukaryotes, but the principles underlying the genomic distribution and evolution of uORFs remain poorly understood. Here, we analyze ~17 million putative canonical uORFs in 478 eukaryotic species that span most of the extant taxa of eukaryote...
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Determinants of genome-wide distribution and evolution of uORFs in eukaryotes
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TN_cdi_doaj_primary_oai_doaj_org_article_13fd6825b17a45a79453f599f7700cc2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13fd6825b17a45a79453f599f7700cc2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21394-y