Paternal-age-related de novo mutations and risk for five disorders
Paternal-age-related de novo mutations and risk for five disorders
About this item
Full title
Author / Creator
Taylor, Jacob L. , Debost, Jean-Christophe P. G. , Morton, Sarah U. , Wigdor, Emilie M. , Heyne, Henrike O. , Lal, Dennis , Howrigan, Daniel P. , Bloemendal, Alex , Larsen, Janne T. , Kosmicki, Jack A. , Weiner, Daniel J. , Homsy, Jason , Seidman, Jonathan G. , Seidman, Christine E. , Agerbo, Esben , McGrath, John J. , Mortensen, Preben Bo , Petersen, Liselotte , Daly, Mark J. and Robinson, Elise B.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
There are established associations between advanced paternal age and offspring risk for psychiatric and developmental disorders. These are commonly attributed to genetic mutations, especially de novo single nucleotide variants (dnSNVs), that accumulate with increasing paternal age. However, the actual magnitude of risk from such mutations in the ma...
Alternative Titles
Full title
Paternal-age-related de novo mutations and risk for five disorders
Authors, Artists and Contributors
Author / Creator
Debost, Jean-Christophe P. G.
Morton, Sarah U.
Wigdor, Emilie M.
Heyne, Henrike O.
Lal, Dennis
Howrigan, Daniel P.
Bloemendal, Alex
Larsen, Janne T.
Kosmicki, Jack A.
Weiner, Daniel J.
Homsy, Jason
Seidman, Jonathan G.
Seidman, Christine E.
Agerbo, Esben
McGrath, John J.
Mortensen, Preben Bo
Petersen, Liselotte
Daly, Mark J.
Robinson, Elise B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_13fdbd2aa6194902a4f369cc6b8b90a5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_13fdbd2aa6194902a4f369cc6b8b90a5
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11039-6
