A Cell-Based Evaluation of the Tyrosinase-Mediated Metabolic Activation of Leukoderma-Inducing Pheno...
A Cell-Based Evaluation of the Tyrosinase-Mediated Metabolic Activation of Leukoderma-Inducing Phenols, II: The Depletion of Nrf2 Augments the Cytotoxic Effect Evoked by Tyrosinase in Melanogenic Cells
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Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Chemical leukoderma is a disorder induced by chemicals such as rhododendrol and monobenzone. These compounds possess a
-substituted phenol moiety and undergo oxidation into highly reactive and toxic
-quinone metabolites by tyrosinase. This metabolic activation plays a critical role in the development of leukoderma through the production of da...
Alternative Titles
Full title
A Cell-Based Evaluation of the Tyrosinase-Mediated Metabolic Activation of Leukoderma-Inducing Phenols, II: The Depletion of Nrf2 Augments the Cytotoxic Effect Evoked by Tyrosinase in Melanogenic Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_1402e4214f4d42bab2b11e08401293b8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1402e4214f4d42bab2b11e08401293b8
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom15010114
