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Large molecules from the cerebrospinal fluid enter the optic nerve but not the retina of mice

Large molecules from the cerebrospinal fluid enter the optic nerve but not the retina of mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_140b21ad8e6848179326dc2c9943a577

Large molecules from the cerebrospinal fluid enter the optic nerve but not the retina of mice

About this item

Full title

Large molecules from the cerebrospinal fluid enter the optic nerve but not the retina of mice

Publisher

England: BioMed Central Ltd

Journal title

Fluids and barriers of the CNS, 2024-01, Vol.21 (1), p.1-12, Article 1

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

It has been proposed that cerebrospinal fluid (CSF) can enter and leave the retina and optic nerve along perivascular spaces surrounding the central retinal vessels as part of an aquaporin-4 (AQP4) dependent ocular 'glymphatic' system. Here, we injected fluorescent dextrans and antibodies into the CSF of mice at the cisterna magna and measured thei...

Alternative Titles

Full title

Large molecules from the cerebrospinal fluid enter the optic nerve but not the retina of mice

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_140b21ad8e6848179326dc2c9943a577

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_140b21ad8e6848179326dc2c9943a577

Other Identifiers

ISSN

2045-8118

E-ISSN

2045-8118

DOI

10.1186/s12987-023-00506-4

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