Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk vari...
Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk variants
About this item
Full title
Author / Creator
PRECISEADS Clinical Consortium , PRECISEADS Flow Cytometry Study Group , Castellini-Pérez, Olivia , Povedano, Elena , Barturen, Guillermo , Martínez-Bueno, Manuel , Iakovliev, Andrii , Kerick, Martin , López-Domínguez, Raúl , Marañón, Concepción , Martín, Javier , Ballestar, Esteban , Borghi, María Orietta , Qiu, Weiliang , Zhu, Cheng , Shankara, Srinivas , Spiliopoulou, Athina , de Rinaldis, Emanuele , Carnero-Montoro, Elena and Alarcón-Riquelme, Marta E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The heterogeneity of systemic lupus erythematosus (SLE) can be explained by epigenetic alterations that disrupt transcriptional programs mediating environmental and genetic risk. This study evaluated the epigenetic contribution to SLE heterogeneity considering molecular and serological subtypes, genetics and transcriptional status, followed by drug...
Alternative Titles
Full title
Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk variants
Authors, Artists and Contributors
Author / Creator
PRECISEADS Flow Cytometry Study Group
Castellini-Pérez, Olivia
Povedano, Elena
Barturen, Guillermo
Martínez-Bueno, Manuel
Iakovliev, Andrii
Kerick, Martin
López-Domínguez, Raúl
Marañón, Concepción
Martín, Javier
Ballestar, Esteban
Borghi, María Orietta
Qiu, Weiliang
Zhu, Cheng
Shankara, Srinivas
Spiliopoulou, Athina
de Rinaldis, Emanuele
Carnero-Montoro, Elena
Alarcón-Riquelme, Marta E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_142e1626384c4d3d9b97c0f758239917
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_142e1626384c4d3d9b97c0f758239917
Other Identifiers
ISSN
2056-7944
E-ISSN
2056-7944
DOI
10.1038/s41525-024-00420-0
