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Gallbladder wall abnormality in biliary atresia of mouse Sox17 +/− neonates and human infants

Gallbladder wall abnormality in biliary atresia of mouse Sox17 +/− neonates and human infants

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_143f6070b1804a1cb8fe24296ed6b05d

Gallbladder wall abnormality in biliary atresia of mouse Sox17 +/− neonates and human infants

About this item

Full title

Gallbladder wall abnormality in biliary atresia of mouse Sox17 +/− neonates and human infants

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2020-04, Vol.13 (4)

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Biliary atresia (BA) is characterized by the inflammation and obstruction of the extrahepatic bile ducts (EHBDs) in newborn infants. SOX17 is a master regulator of the fetal EHBDs formation. In mouse Sox17+/− BA models, SOX17 reduction causes cell-autonomous epithelial shedding together with the ectopic appearance of SOX9-positive cystic duct-like...

Alternative Titles

Full title

Gallbladder wall abnormality in biliary atresia of mouse Sox17 +/− neonates and human infants

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_143f6070b1804a1cb8fe24296ed6b05d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_143f6070b1804a1cb8fe24296ed6b05d

Other Identifiers

ISSN

1754-8403

E-ISSN

1754-8411

DOI

10.1242/dmm.042119

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