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Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardia...

Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardia...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15192fdd21664bbd8a8633584b174318

Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: protocol for the HyperCarD2 randomised, crossover trial

About this item

Full title

Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: protocol for the HyperCarD2 randomised, crossover trial

Publisher

London: British Medical Journal Publishing Group

Journal title

BMJ open, 2022-08, Vol.12 (8), p.e054100-e054100

Language

English

Formats

Publication information

Publisher

London: British Medical Journal Publishing Group

More information

Scope and Contents

Contents

IntroductionType 2 diabetes (T2D) is characterised by elevated plasma glucose, free fatty acid (FFA) and insulin concentrations, and this metabolic profile is linked to diabetic cardiomyopathy, a diastolic dysfunction at first and increased cardiovascular disease (CVD) risk. Shifting cardiac metabolism towards glucose utilisation has been suggested...

Alternative Titles

Full title

Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: protocol for the HyperCarD2 randomised, crossover trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_15192fdd21664bbd8a8633584b174318

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15192fdd21664bbd8a8633584b174318

Other Identifiers

ISSN

2044-6055

E-ISSN

2044-6055

DOI

10.1136/bmjopen-2021-054100

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