Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle
Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Brain cells continuously produce and release protons into the extracellular space, with the rate of acid production corresponding to the levels of neuronal activity and metabolism. Efficient buffering and removal of excess H
+
is essential for brain function, not least because all the electrogenic and biochemical machinery of synaptic transmi...
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Full title
Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle
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TN_cdi_doaj_primary_oai_doaj_org_article_1524bdcca8db439a89cd7a17717a5a6c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1524bdcca8db439a89cd7a17717a5a6c
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18756-3
