WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-medi...
WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation
About this item
Full title
Author / Creator
Xu, Mingang , Horrell, Jeremy , Snitow, Melinda , Cui, Jiawei , Gochnauer, Heather , Syrett, Camille M. , Kallish, Staci , Seykora, John T. , Liu, Fei , Gaillard, Dany , Katz, Jonathan P. , Kaestner, Klaus H. , Levin, Brooke , Mansfield, Corinne , Douglas, Jennifer E. , Cowart, Beverly J. , Tordoff, Michael , Liu, Fang , Zhu, Xuming , Barlow, Linda A. , Rubin, Adam I. , McGrath, John A. , Morrisey, Edward E. , Chu, Emily Y. and Millar, Sarah E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Human
WNT10A
mutations are associated with developmental tooth abnormalities and adolescent onset of a broad range of ectodermal defects. Here we show that β-catenin pathway activity and adult epithelial progenitor proliferation are reduced in the absence of WNT10A, and identify Wnt-active self-renewing stem cells in affected tissues includin...
Alternative Titles
Full title
WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation
Authors, Artists and Contributors
Author / Creator
Horrell, Jeremy
Snitow, Melinda
Cui, Jiawei
Gochnauer, Heather
Syrett, Camille M.
Kallish, Staci
Seykora, John T.
Liu, Fei
Gaillard, Dany
Katz, Jonathan P.
Kaestner, Klaus H.
Levin, Brooke
Mansfield, Corinne
Douglas, Jennifer E.
Cowart, Beverly J.
Tordoff, Michael
Liu, Fang
Zhu, Xuming
Barlow, Linda A.
Rubin, Adam I.
McGrath, John A.
Morrisey, Edward E.
Chu, Emily Y.
Millar, Sarah E.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_155ddb06076c415fa01075d340f6d738
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_155ddb06076c415fa01075d340f6d738
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15397
