Proton pump inhibitors reduce chemotherapeutic hepatotoxicity and enhance hepatic uptake and accumul...
Proton pump inhibitors reduce chemotherapeutic hepatotoxicity and enhance hepatic uptake and accumulation of drug-loaded extracellular vesicles
About this item
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Author / Creator
Li, Mengyu , Yuan, Weiyi , Kong, Xianghui , Wu, Hao , Cai, Zhijian , Zhu, Weiguo and Lu, Xinliang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Extracellular vesicles (EVs) are involved in the progression of various diseases. Tumor cell-derived EVs (TEVs) are a particular concern, as they can induce fatty liver by promoting liver macrophages to secrete tumor necrosis factor (TNF), thus enhancing the toxicity of chemotherapy. Therefore, reducing pathogenic EV production is a potential strat...
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Full title
Proton pump inhibitors reduce chemotherapeutic hepatotoxicity and enhance hepatic uptake and accumulation of drug-loaded extracellular vesicles
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_157c6392a85749c0a6a2afe72910c377
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_157c6392a85749c0a6a2afe72910c377
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-75775-6
