Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration
Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration
About this item
Full title
Author / Creator
Roubeix, Christophe , Nous, Caroline , Augustin, Sébastien , Ronning, Kaitryn E , Mathis, Thibaud , Blond, Frédéric , Lagouge-Roussey, Pauline , Crespo-Garcia, Sergio , Sullivan, Patrick M , Gautier, Emmanuel L , Reichhart, Nadine , Sahel, José-Alain , Burns, Marie E , Paques, Michel , Sørensen, Torben Lykke , Strauss, Olaf , Guillonneau, Xavier , Delarasse, Cécile and Sennlaub, Florian
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Age-related macular degeneration (AMD) is invariably associated with the chronic accumulation of activated mononuclear phagocytes in the subretinal space. The mononuclear phagocytes are composed of microglial cells but also of monocyte-derived cells, which promote photoreceptor degeneration and choroidal neovascularization. Infiltrating blood monoc...
Alternative Titles
Full title
Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration
Authors, Artists and Contributors
Author / Creator
Nous, Caroline
Augustin, Sébastien
Ronning, Kaitryn E
Mathis, Thibaud
Blond, Frédéric
Lagouge-Roussey, Pauline
Crespo-Garcia, Sergio
Sullivan, Patrick M
Gautier, Emmanuel L
Reichhart, Nadine
Sahel, José-Alain
Burns, Marie E
Paques, Michel
Sørensen, Torben Lykke
Strauss, Olaf
Guillonneau, Xavier
Delarasse, Cécile
Sennlaub, Florian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_15a2fe8398d24307833b4ae362a8cd9b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15a2fe8398d24307833b4ae362a8cd9b
Other Identifiers
ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-024-03011-z
