Copy number architectures define treatment-mediated selection of lethal prostate cancer clones
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones
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Full title
Author / Creator
PEACE consortium , Hasan, A. M. Mahedi , Cremaschi, Paolo , Wetterskog, Daniel , Jayaram, Anuradha , Wong, Stephen Q. , Williams, Scott , Pasam, Anupama , Trigos, Anna , Trujillo, Blanca , Grist, Emily , Friedrich, Stefanie , Vainauskas, Osvaldas , Parry, Marina , Ismail, Mazlina , Devlies, Wout , Wingate, Anna , Linch, Mark , Naceur-Lombardelli, Cristina , Swanton, Charles , Jamal-Hanjani, Mariam , Lise, Stefano , Sandhu, Shahneen and Attard, Gerhardt
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Despite initial responses to hormone treatment, metastatic prostate cancer invariably evolves to a lethal state. To characterize the intra-patient evolutionary relationships of metastases that evade treatment, we perform genome-wide copy number profiling and bespoke approaches targeting the androgen receptor (AR) on 167 metastatic regions from 11 o...
Alternative Titles
Full title
Copy number architectures define treatment-mediated selection of lethal prostate cancer clones
Authors, Artists and Contributors
Author / Creator
Hasan, A. M. Mahedi
Cremaschi, Paolo
Wetterskog, Daniel
Jayaram, Anuradha
Wong, Stephen Q.
Williams, Scott
Pasam, Anupama
Trigos, Anna
Trujillo, Blanca
Grist, Emily
Friedrich, Stefanie
Vainauskas, Osvaldas
Parry, Marina
Ismail, Mazlina
Devlies, Wout
Wingate, Anna
Linch, Mark
Naceur-Lombardelli, Cristina
Swanton, Charles
Jamal-Hanjani, Mariam
Lise, Stefano
Sandhu, Shahneen
Attard, Gerhardt
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_15b82c9f94984634bd2b43be9ad37a9e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15b82c9f94984634bd2b43be9ad37a9e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-40315-9
