A whole genome screen for HIV restriction factors
A whole genome screen for HIV restriction factors
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Upon cellular entry retroviruses must avoid innate restriction factors produced by the host cell. For human immunodeficiency virus (HIV) human restriction factors, APOBEC3 (apolipoprotein-B-mRNA-editing-enzyme), p21 and tetherin are well characterised.
To identify intrinsic resistance factors to HIV-1 replication we screened 19,121 human genes a...
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Full title
A whole genome screen for HIV restriction factors
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TN_cdi_doaj_primary_oai_doaj_org_article_15c4e956e3324b85b3c288c749e673ca
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15c4e956e3324b85b3c288c749e673ca
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ISSN
1742-4690
E-ISSN
1742-4690
DOI
10.1186/1742-4690-8-94