Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic end...
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment
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Author / Creator
Hagihara, Hideo , Shoji, Hirotaka , Hattori, Satoko , Sala, Giovanni , Takamiya, Yoshihiro , Tanaka, Mika , Ihara, Masafumi , Shibutani, Mihiro , Hatada, Izuho , Hori, Kei , Hoshino, Mikio , Nakao, Akito , Mori, Yasuo , Okabe, Shigeo , Matsushita, Masayuki , Urbach, Anja , Katayama, Yuta , Matsumoto, Akinobu , Nakayama, Keiichi I , Katori, Shota , Sato, Takuya , Iwasato, Takuji , Nakamura, Haruko , Goshima, Yoshio , Raveau, Matthieu , Tatsukawa, Tetsuya , Yamakawa, Kazuhiro , Takahashi, Noriko , Kasai, Haruo , Inazawa, Johji , Nobuhisa, Ikuo , Kagawa, Tetsushi , Taga, Tetsuya , Darwish, Mohamed , Nishizono, Hirofumi , Takao, Keizo , Sapkota, Kiran , Nakazawa, Kazutoshi , Takagi, Tsuyoshi , Fujisawa, Haruki , Sugimura, Yoshihisa , Yamanishi, Kyosuke , Rajagopal, Lakshmi , Hannah, Nanette Deneen , Meltzer, Herbert Y , Yamamoto, Tohru , Wakatsuki, Shuji , Araki, Toshiyuki , Tabuchi, Katsuhiko , Numakawa, Tadahiro , Kunugi, Hiroshi , Huang, Freesia L , Hayata-Takano, Atsuko , Hashimoto, Hitoshi , Tamada, Kota , Takumi, Toru , Kasahara, Takaoki , Kato, Tadafumi , Graef, Isabella A , Crabtree, Gerald R , Asaoka, Nozomi , Hatakama, Hikari , Kaneko, Shuji , Kohno, Takao , Hattori, Mitsuharu , Hoshiba, Yoshio , Miyake, Ryuhei , Obi-Nagata, Kisho , Hayashi-Takagi, Akiko , Becker, Léa J , Yalcin, Ipek , Hagino, Yoko , Kotajima-Murakami, Hiroko , Moriya, Yuki , Ikeda, Kazutaka , Kim, Hyopil , Kaang, Bong-Kiun , Otabi, Hikari , Yoshida, Yuta , Toyoda, Atsushi , Komiyama, Noboru H , Grant, Seth GN , Ida-Eto, Michiru , Narita, Masaaki , Matsumoto, Ken-ichi , Okuda-Ashitaka, Emiko , Ohmori, Iori , Shimada, Tadayuki , Yamagata, Kanato , Ageta, Hiroshi , Tsuchida, Kunihiro , Inokuchi, Kaoru , Sassa, Takayuki , Kihara, Akio , Fukasawa, Motoaki , Usuda, Nobuteru , Katano, Tayo , Tanaka, Teruyuki , Yoshihara, Yoshihiro and Igarashi, Michihiro
Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
Increased levels of lactate, an end-product of glycolysis, have been proposed as a potential surrogate marker for metabolic changes during neuronal excitation. These changes in lactate levels can result in decreased brain pH, which has been implicated in patients with various neuropsychiatric disorders. We previously demonstrated that such alterati...
Alternative Titles
Full title
Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment
Authors, Artists and Contributors
Author / Creator
Shoji, Hirotaka
Hattori, Satoko
Sala, Giovanni
Takamiya, Yoshihiro
Tanaka, Mika
Ihara, Masafumi
Shibutani, Mihiro
Hatada, Izuho
Hori, Kei
Hoshino, Mikio
Nakao, Akito
Mori, Yasuo
Okabe, Shigeo
Matsushita, Masayuki
Urbach, Anja
Katayama, Yuta
Matsumoto, Akinobu
Nakayama, Keiichi I
Katori, Shota
Sato, Takuya
Iwasato, Takuji
Nakamura, Haruko
Goshima, Yoshio
Raveau, Matthieu
Tatsukawa, Tetsuya
Yamakawa, Kazuhiro
Takahashi, Noriko
Kasai, Haruo
Inazawa, Johji
Nobuhisa, Ikuo
Kagawa, Tetsushi
Taga, Tetsuya
Darwish, Mohamed
Nishizono, Hirofumi
Takao, Keizo
Sapkota, Kiran
Nakazawa, Kazutoshi
Takagi, Tsuyoshi
Fujisawa, Haruki
Sugimura, Yoshihisa
Yamanishi, Kyosuke
Rajagopal, Lakshmi
Hannah, Nanette Deneen
Meltzer, Herbert Y
Yamamoto, Tohru
Wakatsuki, Shuji
Araki, Toshiyuki
Tabuchi, Katsuhiko
Numakawa, Tadahiro
Kunugi, Hiroshi
Huang, Freesia L
Hayata-Takano, Atsuko
Hashimoto, Hitoshi
Tamada, Kota
Takumi, Toru
Kasahara, Takaoki
Kato, Tadafumi
Graef, Isabella A
Crabtree, Gerald R
Asaoka, Nozomi
Hatakama, Hikari
Kaneko, Shuji
Kohno, Takao
Hattori, Mitsuharu
Hoshiba, Yoshio
Miyake, Ryuhei
Obi-Nagata, Kisho
Hayashi-Takagi, Akiko
Becker, Léa J
Yalcin, Ipek
Hagino, Yoko
Kotajima-Murakami, Hiroko
Moriya, Yuki
Ikeda, Kazutaka
Kim, Hyopil
Kaang, Bong-Kiun
Otabi, Hikari
Yoshida, Yuta
Toyoda, Atsushi
Komiyama, Noboru H
Grant, Seth GN
Ida-Eto, Michiru
Narita, Masaaki
Matsumoto, Ken-ichi
Okuda-Ashitaka, Emiko
Ohmori, Iori
Shimada, Tadayuki
Yamagata, Kanato
Ageta, Hiroshi
Tsuchida, Kunihiro
Inokuchi, Kaoru
Sassa, Takayuki
Kihara, Akio
Fukasawa, Motoaki
Usuda, Nobuteru
Katano, Tayo
Tanaka, Teruyuki
Yoshihara, Yoshihiro
Igarashi, Michihiro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_15de117935204a21a8487997042e8094
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15de117935204a21a8487997042e8094
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.89376
