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Cryo-EM structure of alpha-synuclein fibrils

Cryo-EM structure of alpha-synuclein fibrils

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15f64f3dc9904bdab0ab54b34b6e6cb9

Cryo-EM structure of alpha-synuclein fibrils

About this item

Full title

Cryo-EM structure of alpha-synuclein fibrils

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2018-07, Vol.7

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Parkinson's disease is a progressive neuropathological disorder that belongs to the class of synucleinopathies, in which the protein alpha-synuclein is found at abnormally high concentrations in affected neurons. Its hallmark are intracellular inclusions called Lewy bodies and Lewy neurites. We here report the structure of cytotoxic alpha-synuclein...

Alternative Titles

Full title

Cryo-EM structure of alpha-synuclein fibrils

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_15f64f3dc9904bdab0ab54b34b6e6cb9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_15f64f3dc9904bdab0ab54b34b6e6cb9

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.36402

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