NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-s...
NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The increasing availability of single-cell data revolutionizes the understanding of biological mechanisms at cellular resolution. For differential expression analysis in multi-subject single-cell data, negative binomial mixed models account for both subject-level and cell-level overdispersions, but are computationally demanding. Here, we propose an...
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NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data
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TN_cdi_doaj_primary_oai_doaj_org_article_1604a175b02d438a8389ecd99650f39c
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1604a175b02d438a8389ecd99650f39c
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-021-02146-6
