Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future
Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer’s disease (AD), and its accumulation has been considered as the molecular driver of Alzheimer’s pathogenesis and progression. Aβ has been the prime target for the development of AD therapy. However, the repeated failures of Aβ-targeted clinical trials have cast considerab...
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Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future
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TN_cdi_doaj_primary_oai_doaj_org_article_162ca51a0a0a4d50ad4d17a242413b57
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_162ca51a0a0a4d50ad4d17a242413b57
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ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-023-01484-7