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Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future

Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_162ca51a0a0a4d50ad4d17a242413b57

Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future

About this item

Full title

Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future

Publisher

London: Nature Publishing Group UK

Journal title

Signal transduction and targeted therapy, 2023-06, Vol.8 (1), p.248-248, Article 248

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Amyloid β protein (Aβ) is the main component of neuritic plaques in Alzheimer’s disease (AD), and its accumulation has been considered as the molecular driver of Alzheimer’s pathogenesis and progression. Aβ has been the prime target for the development of AD therapy. However, the repeated failures of Aβ-targeted clinical trials have cast considerab...

Alternative Titles

Full title

Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_162ca51a0a0a4d50ad4d17a242413b57

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_162ca51a0a0a4d50ad4d17a242413b57

Other Identifiers

ISSN

2059-3635,2095-9907

E-ISSN

2059-3635

DOI

10.1038/s41392-023-01484-7

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