HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules
HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules
About this item
Full title
Author / Creator
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
The HIV-1 transactivator protein Tat interacts with the transactivation response element (TAR) at the three-nucleotide UCU bulge to facilitate the recruitment of transcription elongation factor-b (P-TEFb) and induce the transcription of the integrated proviral genome. Therefore, the Tat–TAR interaction, unique to the virus, is a promising target fo...
Alternative Titles
Full title
HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_16630d3bc2964e1d8a47b520074e38ee
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_16630d3bc2964e1d8a47b520074e38ee
Other Identifiers
ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph17010033
