Splicing is an alternate oncogenic pathway activation mechanism in glioma
Splicing is an alternate oncogenic pathway activation mechanism in glioma
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
High-grade diffuse glioma (HGG) is the leading cause of brain tumour death. While the genetic drivers of HGG have been well described, targeting these has thus far had little impact on survival suggesting other mechanisms are at play. Here we interrogate the alternative splicing landscape of pediatric and adult HGG through multi-omic analyses, unco...
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Full title
Splicing is an alternate oncogenic pathway activation mechanism in glioma
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TN_cdi_doaj_primary_oai_doaj_org_article_16682e61ebb34dd9b0ee5d0b70707f1e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_16682e61ebb34dd9b0ee5d0b70707f1e
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28253-4
