The Importance of the Dissociation Rate in Ion Channel Blocking
The Importance of the Dissociation Rate in Ion Channel Blocking
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Understanding the relationships between the rates and dynamics of current wave forms under voltage clamp conditions is essential for understanding phenomena such as state-dependence and use-dependence, which are fundamental for the action of drugs used as anti-epileptics, anti-arrhythmics, and anesthetics. In the present study, we mathematically an...
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Full title
The Importance of the Dissociation Rate in Ion Channel Blocking
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TN_cdi_doaj_primary_oai_doaj_org_article_167094c6fa424ab58247d5c90bbafc38
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_167094c6fa424ab58247d5c90bbafc38
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2018.00033
