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Differential Regulation of Echinocandin Targets Fks1 and Fks2 in Candida glabrata by the Post-Transc...

Differential Regulation of Echinocandin Targets Fks1 and Fks2 in Candida glabrata by the Post-Transc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_167ff5ae15ea416fa5cd371c81c5239e

Differential Regulation of Echinocandin Targets Fks1 and Fks2 in Candida glabrata by the Post-Transcriptional Regulator Ssd1

About this item

Full title

Differential Regulation of Echinocandin Targets Fks1 and Fks2 in Candida glabrata by the Post-Transcriptional Regulator Ssd1

Publisher

Basel: MDPI AG

Journal title

Journal of fungi (Basel), 2020-09, Vol.6 (3), p.143

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Invasive infections caused by the opportunistic pathogen Candida glabrata are treated with echinocandin antifungals that target β-1,3-glucan synthase, an enzyme critical for fungal cell wall biosynthesis. Echinocandin resistance develops upon mutation of genes (FKS1 or FKS2) that encode the glucan synthase catalytic subunits. We have analyzed cellu...

Alternative Titles

Full title

Differential Regulation of Echinocandin Targets Fks1 and Fks2 in Candida glabrata by the Post-Transcriptional Regulator Ssd1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_167ff5ae15ea416fa5cd371c81c5239e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_167ff5ae15ea416fa5cd371c81c5239e

Other Identifiers

ISSN

2309-608X

E-ISSN

2309-608X

DOI

10.3390/jof6030143

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