Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype...
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity
About this item
Full title
Author / Creator
Dalton, Rachel , Lee, Seung‐been , Claw, Katrina G. , Prasad, Bhagwat , Phillips, Brian R. , Shen, Danny D. , Wong, Lai Hong , Fade, Mitch , McDonald, Matthew G. , Dunham, Maitreya J. , Fowler, Douglas M. , Rettie, Allan E. , Schuetz, Erin , Thornton, Timothy A. , Nickerson, Deborah A. , Gaedigk, Andrea , Thummel, Kenneth E. and Woodahl, Erica L.
Publisher
United States: John Wiley and Sons Inc
Journal title
Language
English
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Publication information
Publisher
United States: John Wiley and Sons Inc
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More information
Scope and Contents
Contents
The cytochrome P450 2D6 (CYP2D6) gene locus is challenging to accurately genotype due to numerous single nucleotide variants and complex structural variation. Our goal was to determine whether the CYP2D6 genotype‐phenotype correlation is improved when diplotype assignments incorporate structural variation, identified by the bioinformatics tool Star...
Alternative Titles
Full title
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity
Authors, Artists and Contributors
Author / Creator
Lee, Seung‐been
Claw, Katrina G.
Prasad, Bhagwat
Phillips, Brian R.
Shen, Danny D.
Wong, Lai Hong
Fade, Mitch
McDonald, Matthew G.
Dunham, Maitreya J.
Fowler, Douglas M.
Rettie, Allan E.
Schuetz, Erin
Thornton, Timothy A.
Nickerson, Deborah A.
Gaedigk, Andrea
Thummel, Kenneth E.
Woodahl, Erica L.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_16a9484280914410be57114d167f3ce5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_16a9484280914410be57114d167f3ce5
Other Identifiers
ISSN
1752-8054
E-ISSN
1752-8062
DOI
10.1111/cts.12695
