Log in to save to my catalogue

Genetic association and causal inference converge on hyperglycaemia as a modifiable factor to improv...

Genetic association and causal inference converge on hyperglycaemia as a modifiable factor to improv...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_16e00623321540a6a30d5172abea081f

Genetic association and causal inference converge on hyperglycaemia as a modifiable factor to improve lung function

About this item

Full title

Genetic association and causal inference converge on hyperglycaemia as a modifiable factor to improve lung function

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2021-03, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Measures of lung function are heritable, and thus, we sought to utilise genetics to propose drug-repurposing candidates that could improve respiratory outcomes. Lung function measures were found to be genetically correlated with seven druggable biochemical traits, with further evidence of a causal relationship between increased fasting glucose and...

Alternative Titles

Full title

Genetic association and causal inference converge on hyperglycaemia as a modifiable factor to improve lung function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_16e00623321540a6a30d5172abea081f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_16e00623321540a6a30d5172abea081f

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.63115

How to access this item