The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin
The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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The huntingtin-associated protein 40 (HAP40) abundantly interacts with huntingtin (HTT), the protein that is altered in Huntington's disease (HD). Therefore, we analysed the evolution of HAP40 and its interaction with HTT.
We found that in amniotes HAP40 is encoded by a single-exon gene, whereas in all other organisms it is expressed from multi-...
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Full title
The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin
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TN_cdi_doaj_primary_oai_doaj_org_article_16f3a3a125f343eab0ffd6895c8d452e
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_16f3a3a125f343eab0ffd6895c8d452e
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ISSN
1471-2148
E-ISSN
1471-2148,2730-7182
DOI
10.1186/s12862-020-01705-5
