Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor pro...
Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer
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England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs from M2 (pro-tumor) to M1 (anti-tumor) phenotypes represents an important therapeutic goal. We have previously shown that upregulated NF-kappaB (NF-κB) signaling in macrophages promotes M1 polar...
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Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_1721307f4b964b83b11c876f207a8f61
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_1721307f4b964b83b11c876f207a8f61
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-020-07450-8
